I've got 200 and 300's both in XR and norm..
Both have a thick coating, and can get them prep'd to shoot without cooking them as long as I get a pocket knife and scrape off that almost thick sticky top layer, it almost peels off in places.. those having clogging issues, make sure u scrape it off, you may want to cook it, I don't, I norm use a 3ml barrel and normal screw tip 27g and a rollie filter.. I've got/tried wheel filters and the newer "steri-filters" but norm don't use them, I'm stuck in my ways as I both shoot and eat all my prescribed meds.. Valium..Xanax, seroquel, Endone, methadone, and physeptone tabs..
Had a few swollen sites but get over them pretty fast even with no immune sys.. Been doing it many years..
I know there is more "harm reduction" I could follow.. But yes you can shoot seroquel..
I know someone that has lost there arm, and someone that almost lost a leg.. Just be careful, if your new to IV'ng then do some research first!!!
Taking 300mg orally and a few Xanax and couple Valium, and my methadone gets me on the nod pretty good.. Guess ev is diff, I've got a high tolerance and on 210 of methadone..
Unless u have a needle addiction or your new to the scene, just eat em "IMO"