To treat perioral dermatitis, anti-inflammatory systemic and/or topical therapy is required. It is best to consult a dermatologist to evaluate provoking factors and to determine the individualized treatment.
In severe forms of perioral dermatitis, oral treatment using anti-acne drugs is necessary. The drugs of choice are doxycycline or tetracycline and minocycline. In unresponsive and granulomatous forms, oral isotretinoin may be used. In minor cases, as well as in children and pregnant women, individualized topical therapy is generally recommended.
Anti-inflammatory agents such as metronidazole and erythromycin are administered in a non-greasy base like gel, lotion, or cream, but never ointments.
Avoid using cosmetics on your face, especially on the area of infection. Use a mild cleanser to wash your face.