I have posted before. I am now four years with this med. Within the last 4 months, I have begun to tear and crack nails. I don't remember how long I have been without a thumb nail. You don't know how important it is until its gone. May hair continues to slowly fall out (not genetic). The fatigue is still awful. For the past three winters, I have gotten colds that have lasted forever. They are accompanied by a cough that goes for months. Pul. specialist says my lungs are fine. I just cough. Chrohn's is better. All else worse.