This MEDICINE has made an important difference. I was taking all kinds of fiber, and still had to use laxatives to go more than once per week. Now I go at least every 2-3 days and have a much softer stool. This was done with help of the wonderful tablet. And I have only had 1 event of IBS pain since initializing this, and it was not as strict. I still have a little mess detection to take the pill before I start eating specially at the sunset meal. The other thing that has to be aware of the medicine is its cost. I have good insurance, costs me $30, so I can manage the cost. If there was no insurance, it would cost about $150/month, since my doctor wants me to stay on the drug history the optional duration of 12 weeks. But nothing can be done I have to continue until my doctor asks me to stop.