I had arthritis and depression and this drug was a life saver. It took away all my pain and all my depression. I had no idea it was an anti depressant but I realized later that I was feeling a lot better after taking the drug. I highly recommend it for other people too. It is a great drug and it works so well with the pain. I did not have any flares after taking it. I am very satisfied with it. Sadly, it does not work on every body and now it is very hard to get a prescription because of the side effects.