Celexa was not at all effective for me. I used gamut of medicines, Zoloft, serzone, Wellbutrin before going to Celexa. From all these medicines, I got some strange side effects. I had huge expectation on Celexa, but it was not reached near my expectations. I could not say it did not work on me because it reduced depression and other problems related with GI. I had nausea in its extreme and diarrhea, both of them made my life horrible than hell. I read from a medical journal that these all are the common side effects caused by SSRIs. In these, loss of fluid and imbalance of electrolyte may cause for the death of the user. After reading about Celexa I stopped it and I moved to Remeron which acts best on me.