I am a victim of depression and had tried all kinds of drugs like Prozac, Celaxa, Paxil and Zoloft with absolutely no effect. It was the fifth drug Wellbutrin XL that gave me my life back. It brought about a tremendous change in me. I used to have one 300 mg pill daily and it was very effective for my symptoms and worked like a charm. I just cannot make you understand the importance of making your doctor changing your prescription to Wellbutrin. This drug does take a little bit of time to start working. As I started on a low dose and slowly hiked it up, the adverse effects were quite bearable.